Gene

sgk3

ID

ZDB-GENE-070424-62

Name

serum/glucocorticoid regulated kinase family member 3

Symbol

sgk3 Nomenclature History

Previous Names

zgc:162253

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to enable potassium channel regulator activity and protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in early endosome and recycling endosome. Orthologous to several human genes including SGK3 (serum/glucocorticoid regulated kinase family member 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sgk3 Human Ortholog

No data available

Associated With sgk3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR000961	AGC-kinase, C-terminal
Domain	IPR001683	Phox homology
Domain	IPR017892	Protein kinase, C-terminal
Domain	IPR037709	Serine/threonine-protein kinase Sgk3, catalytic domain
Domain	IPR037900	CISK, PX domain
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR036871	PX domain superfamily