Gene

rab8a

ID

ZDB-GENE-070424-36

Name

RAB8A, member RAS oncogene family

Symbol

rab8a Nomenclature History

Previous Names

rab8 (1)
zgc:162699

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable GTPase activity. Involved in melanosome transport. Acts upstream of or within photoreceptor cell outer segment organization. Predicted to be located in endosome membrane and phagocytic vesicle membrane. Predicted to be active in cytoplasmic vesicle and plasma membrane. Is expressed in eye. Orthologous to human RAB8A (RAB8A, member RAS oncogene family).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rab8a Human Ortholog

No data available

Associated With rab8a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR005225	Small GTP-binding domain
Family	IPR001806	Small GTPase
Family	IPR050305	Small GTPase superfamily, Rab
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase