Gene

nlrp3

ID
ZDB-GENE-070424-110
Name
NLR family pyrin domain containing 3
Symbol
nlrp3 Nomenclature History
Previous Names
  • si:ch211-114l13.10
  • si:dkey-156m2.3
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
null
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
1 - 4 of 4
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-nlrp3
    Tyrkalska et al., 2022
    MO1-nlrp3N/A (2)
    1 - 2 of 2
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    Human Disease
    Associated With nlrp3 Human Ortholog
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    autosomal dominant nonsyndromic deafness 34 Alliance Deafness, autosomal dominant 34, with or without inflammation 617772
    CINCA Syndrome Alliance CINCA syndrome 607115
    familial cold autoinflammatory syndrome 1 Alliance Familial cold inflammatory syndrome 1 120100
    Muckle-Wells syndrome Alliance Muckle-Wells syndrome 191900
    Keratoendothelitis fugax hereditaria 148200
    1 - 5 of 5
    Associated With nlrp3 Via Experimental Models
    No data available
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    Type InterPro ID Name
    Domain IPR001870 B30.2/SPRY domain
    Domain IPR003877 SPRY domain
    Domain IPR003879 Butyrophylin-like, SPRY domain
    Domain IPR004020 DAPIN domain
    Domain IPR006574 SPRY-associated
    1 - 5 of 16 Show all
    Domain Details Per Protein
    Protein Length B30.2/SPRY domain B30.2/SPRY domain superfamily Butyrophylin-like, SPRY domain Concanavalin A-like lectin/glucanase domain superfamily DAPIN domain Death-like domain superfamily Leucine-rich repeat Leucine-rich repeat domain superfamily NACHT-associated domain NACHT, LRR and PYD domains-containing protein, helical domain HD2 NACHT nucleoside triphosphatase NOD1/2, winged helix domain NOD-like receptor (NLR) P-loop containing nucleoside triphosphate hydrolase SPRY-associated SPRY domain
    UniProtKB:A0A8M6YY09 1121
    1 - 1 of 1
    Transcripts
    Genome Browsers
    Genome Build: GRCz11Chromosome: 1
    Type Name Annotation Method Has Havana Data Length (nt) Analysis
    mRNA si:dkey-156m2.3-201 (1) Ensembl 6,595 nt
    1 - 1 of 1
    Interactions and Pathways
    No data available
    Antibodies
    No data available
    Plasmids
    No data available
    Constructs
    No data available
    Marker Relationships
    Relationship Marker Type Marker Accession Numbers Citations
    Contained inBACCH211-114L13ZFIN Curated Data
    Contained inBACDKEY-156M2ZFIN Curated Data
    1 - 2 of 2
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    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanNLRP31
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    Phylogenetic tree (1)
    MouseNlrp311
    Amino acid sequence comparison (1)
    Phylogenetic tree (1)
    Citations
    1 - 7 of 7
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