Gene

taf4b

ID

ZDB-GENE-070424-105

Name

TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor

Symbol

taf4b Nomenclature History

Previous Names

si:ch1073-421n16.1

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable DNA binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to act upstream of or within DNA-templated transcription initiation. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Human ortholog(s) of this gene implicated in spermatogenic failure 13. Orthologous to human TAF4B (TATA-box binding protein associated factor 4b).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With taf4b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
spermatogenic failure 13	Alliance	?Spermatogenic failure 13	615841

Associated With taf4b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003894	TAFH/NHR1
Domain	IPR007900	Transcription initiation factor TFIID component TAF4, C-terminal
Family	IPR045144	Transcription initiation factor TFIID component TAF4
Homologous_superfamily	IPR009072	Histone-fold
Homologous_superfamily	IPR037249	TAFH/NHR1 domain superfamily

Domain Details Per Protein

Protein	Length	Histone-fold	TAFH/NHR1	TAFH/NHR1 domain superfamily	Transcription initiation factor TFIID component TAF4	Transcription initiation factor TFIID component TAF4, C-terminal
UniProtKB:A0A8M6YWV6 InterPro	833

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	taf4b-201 (1) Ensembl	Ensembl	2,834 nt	Select Tool ZFIN BLAST
mRNA	taf4b-202 (1) Ensembl	Ensembl	2,798 nt	Select Tool ZFIN BLAST
mRNA	taf4b-203 (1) Ensembl	Ensembl	3,059 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations