Gene

pmvk

ID
ZDB-GENE-070410-91
Name
phosphomevalonate kinase
Symbol
pmvk Nomenclature History
Previous Names
  • zgc:162701
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have phosphomevalonate kinase activity. Predicted to be involved in cholesterol biosynthetic process and isopentenyl diphosphate biosynthetic process, mevalonate pathway. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human PMVK (phosphomevalonate kinase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Pradhan et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pmvk Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Porokeratosis 1, multiple types 175800
Associated With pmvk Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR005919 Higher eukaryotic phosphomevalonate kinase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Higher eukaryotic phosphomevalonate kinase P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A4IGD4 199
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA pmvk-201 (1) Havana 2762 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations