Gene

tgfbrap1

ID

ZDB-GENE-070410-66

Name

transforming growth factor, beta receptor associated protein 1

Symbol

tgfbrap1 Nomenclature History

Previous Names

zgc:162302

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to be involved in autophagy and endosomal vesicle fusion. Predicted to be located in early endosome. Predicted to be active in cytoplasm and membrane. Orthologous to human TGFBRAP1 (transforming growth factor beta receptor associated protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Zhang et al., 2019

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tgfbrap1 Human Ortholog

No data available

Associated With tgfbrap1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001180	Citron homology (CNH) domain
Domain	IPR019452	Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1
Domain	IPR019453	Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated zinc finger domain
Family	IPR032914	Vam6/VPS39/TRAP1 family
Repeat	IPR000547	Clathrin, heavy chain/VPS, 7-fold repeat

Domain Details Per Protein

Protein	Additional Resources	Length	Citron homology (CNH) domain	Clathrin, heavy chain/VPS, 7-fold repeat	Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1	Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated zinc finger domain	Vam6/VPS39/TRAP1 family
UniProtKB:A4IG72	InterPro	863
UniProtKB:A0A8M3B3B0	InterPro	511

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tgfbrap1-201 (1) Ensembl	Ensembl	2,951 nt	Select Tool ZFIN BLAST
ncRNA	tgfbrap1-002 (1) Ensembl	Ensembl	834 nt	Select Tool ZFIN BLAST
ncRNA	tgfbrap1-003 (1) Ensembl	Ensembl	653 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations