Gene

exoc8

ID

ZDB-GENE-070410-60

Name

exocyst complex component 8

Symbol

exoc8 Nomenclature History

Previous Names

zgc:162287

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to be involved in Golgi to plasma membrane transport and protein localization. Predicted to act upstream of or within exocytosis and protein transport. Predicted to be located in growth cone and perinuclear region of cytoplasm. Predicted to be part of exocyst. Orthologous to human EXOC8 (exocyst complex component 8).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With exoc8 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Neurodevelopmental disorder with microcephaly, seizures, and brain atrophy	619076

Associated With exoc8 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR032403	Exocyst component Exo84, C-terminal
Family	IPR033961	Exocyst complex component Exo84
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR016159	Cullin repeat-like-containing domain superfamily
Homologous_superfamily	IPR042560	Exocyst component Exo84, C-terminal, subdomain 2
Homologous_superfamily	IPR042561	Exocyst component Exo84, C-terminal, subdomain 1

Domain Details Per Protein

Protein	Length	Cullin repeat-like-containing domain superfamily	Exocyst complex component Exo84	Exocyst component Exo84, C-terminal	Exocyst component Exo84, C-terminal, subdomain 1	Exocyst component Exo84, C-terminal, subdomain 2	PH-like domain superfamily	Pleckstrin homology domain
UniProtKB:A4IG64 InterPro	684

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	exoc8-201 (1) Ensembl	Ensembl		2,294 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations