ZFIN ID: ZDB-GENE-070410-25
Gene Name: YME1-like 1b
Gene Symbol: yme1l1b    Nomenclature History

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Previous Names: yme1l1, zgc:162158

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have ATP-dependent peptidase activity. Predicted to be involved in mitochondrion organization and protein quality control for misfolded or incompletely synthesized proteins. Predicted to localize to the mitochondrial inner membrane. Human ortholog(s) of this gene implicated in optic atrophy. Orthologous to human YME1L1 (YME1 like 1 ATPase).
Genome Resources: Alliance (1),  Gene:557907 (1),  Ensembl(GRCz11):ENSDARG00000104401 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH yme1l1b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
optic atrophy 11 Alliance ?Optic atrophy 11 617302
DISEASE ASSOCIATED WITH yme1l1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000642 Peptidase M41
Domain IPR003593 AAA+ ATPase domain
Domain IPR003959 ATPase, AAA-type, core
Conserved_site IPR003960 ATPase, AAA-type, conserved site
Family IPR005936 Peptidase, FtsH
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR037219 Peptidase M41-like
Domain IPR041569 AAA ATPase, AAA+ lid domain
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM yme1l1b No data available
MARKER RELATIONSHIPS
yme1l1b Encodes: [cDNA] MGC:162158 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001089514 (1)
Genomic GenBank:CU655837 (1) 43743 bp
Select Tool
Polypeptide UniProtKB:A4QNU8 (1) 722 aa
Sequence Information (all 11)
ORTHOLOGY for yme1l1b ( Chr: 2 )
CITATIONS (15)