Gene

tnfrsf1b

ID
ZDB-GENE-070410-133
Name
tumor necrosis factor receptor superfamily, member 1B
Symbol
tnfrsf1b Nomenclature History
Previous Names
  • RANK (1)
  • tnfr2 (1)
  • zgc:163064
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Involved in several processes, including peripheral nervous system axon ensheathment; positive regulation of hematopoietic progenitor cell differentiation; and regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to localize to integral component of membrane. Is expressed in several structures, including head; head mesenchyme; hematopoietic system; osteoclast; and scale. Human ortholog(s) of this gene implicated in several diseases, including acne; bone disease (multiple); glomerulonephritis (multiple); lung disease (multiple); and pre-eclampsia. Orthologous to human TNFRSF1B (TNF receptor superfamily member 1B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tnfrsf1b Human Ortholog
No data available
Associated With tnfrsf1b Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001368 TNFR/NGFR cysteine-rich region
Domain IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like
Domain Details Per Protein
Protein Length TNFR/NGFR cysteine-rich region Tyrosine-protein kinase ephrin type A/B receptor-like
UniProtKB:A3KP87 413
UniProtKB:F1RAS9 425
UniProtKB:F8QXP5 286
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations