Gene

nox1

ID
ZDB-GENE-070404-1
Name
NADPH oxidase 1
Symbol
nox1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have superoxide-generating NADPH oxidase activity. Predicted to be involved in defense response; oxidation-reduction process; and superoxide anion generation. Predicted to localize to NADPH oxidase complex. Is expressed in nervous system. Orthologous to human NOX1 (NADPH oxidase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nox1 Human Ortholog
No data available
Associated With nox1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013112 FAD-binding 8
Domain IPR013121 Ferric reductase, NAD binding domain
Domain IPR013130 Ferric reductase transmembrane component-like domain
Domain IPR017927 FAD-binding domain, ferredoxin reductase-type
Family IPR000778 Cytochrome b245, heavy chain
Family IPR050369 Respiratory burst oxidase/Ferric reductase
Homologous_superfamily IPR017938 Riboflavin synthase-like beta-barrel
Homologous_superfamily IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
Domain Details Per Protein
Protein Length Cytochrome b245, heavy chain FAD-binding 8 FAD-binding domain, ferredoxin reductase-type Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Ferric reductase, NAD binding domain Ferric reductase transmembrane component-like domain Respiratory burst oxidase/Ferric reductase Riboflavin synthase-like beta-barrel
UniProtKB:F6NMX7 564
UniProtKB:A7E3K4 576
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nox1-201 (1) Ensembl 3,098 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations