ZFIN is now using GRCz12tu for Genomic Data

Gene

sorbs2b

ID

ZDB-GENE-070308-3

Name

sorbin and SH3 domain containing 2b

Symbol

sorbs2b Nomenclature History

Previous Names

si:ch211-51g4.4 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Acts upstream of or within regulation of heart rate. Predicted to be located in anchoring junction. Predicted to be active in plasma membrane. Is expressed in heart. Orthologous to human SORBS2 (sorbin and SH3 domain containing 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Ding et al., 2020

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Ding et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sorbs2b Human Ortholog

No data available

Associated With sorbs2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001452	SH3 domain
Domain	IPR003127	SoHo domain
Family	IPR050384	Endophilin/SH3RF
Homologous_superfamily	IPR036028	SH3-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:B8A438	InterPro
UniProtKB:A0A8M9Q586	InterPro	1732
UniProtKB:A0A8M9QGR0	InterPro	1540
UniProtKB:A0A8M9PUE0	InterPro	1821
UniProtKB:A0A8M9PUE4	InterPro	1784
UniProtKB:A0A8M6Z492	InterPro	1790
UniProtKB:A0A8M9Q1G6	InterPro	1775
UniProtKB:A0A8M9PN75	InterPro	1822
UniProtKB:A0A8M9PBP1	InterPro	1633
UniProtKB:A0A8M9Q583	InterPro	1781
UniProtKB:A0A8M9QKY3	InterPro	1805
UniProtKB:A0A8M9PN86	InterPro	1773
UniProtKB:A0A8M9Q580	InterPro	1805
UniProtKB:A0A8M9QPG5	InterPro	1718
UniProtKB:A0A8M9QPF5	InterPro	1821
UniProtKB:A0A8M9QKZ6	InterPro	1309
UniProtKB:A0A8M9PBN2	InterPro	1804
UniProtKB:A0A8M9QKZ3	InterPro	1700
UniProtKB:A0A8M9QBH3	InterPro	1784
UniProtKB:A0A8M9PN90	InterPro	1584
UniProtKB:A0A8M9QBI6	InterPro	1584
UniProtKB:A0A8M9QGP3	InterPro	1822
UniProtKB:A0A8M9PZQ6	InterPro	1633
UniProtKB:A0A8M9QGP8	InterPro	1781
UniProtKB:A0A8M9PUF2	InterPro	1540
UniProtKB:A0A8M9QBI2	InterPro	1749
UniProtKB:A0A8M9Q1H4	InterPro	1309
UniProtKB:A0A8M9PZR0	InterPro	1256
UniProtKB:A0A0R4IW85	InterPro	1438
UniProtKB:A0A8M9Q1H1	InterPro	1718
UniProtKB:A0A8M9PZP0	InterPro	1790
UniProtKB:A0A8M9Q589	InterPro	1438
UniProtKB:A0A8M9PBP5	InterPro	1256
UniProtKB:A0A8M9QGQ4	InterPro	1732
UniProtKB:A0A8M9QPG1	InterPro	1775
UniProtKB:A0A8M9QKZ0	InterPro	1773
UniProtKB:A0A8M9PUE8	InterPro	1749
UniProtKB:A0AB32T0S7	InterPro	1539
UniProtKB:A0AB32TLD6	InterPro	1522

Transcripts

Genome Browsers

NCBI Map Viewer

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	sorbs2b-201 (1) Ensembl	Ensembl	7,015 nt	Select Tool ZFIN BLAST
mRNA	sorbs2b-202 (1) Ensembl	Ensembl	924 nt	Select Tool ZFIN BLAST
mRNA	sorbs2b-203 (1) Ensembl	Ensembl	346 nt	Select Tool ZFIN BLAST
mRNA	sorbs2b-204 (1) Ensembl	Ensembl	480 nt	Select Tool ZFIN BLAST
mRNA	sorbs2b-205 (1) Ensembl	Ensembl	5,743 nt	Select Tool ZFIN BLAST
mRNA	sorbs2b-206 (1) Ensembl	Ensembl	4,907 nt	Select Tool ZFIN BLAST
mRNA	sorbs2b-207 (1) Ensembl	Ensembl	5,396 nt	Select Tool ZFIN BLAST
mRNA	sorbs2b-208 (1) Ensembl	Ensembl	4,496 nt	Select Tool ZFIN BLAST
mRNA	sorbs2b-209 (1) Ensembl	Ensembl	5,322 nt	Select Tool ZFIN BLAST
mRNA	sorbs2b-210 (1) Ensembl	Ensembl	2,660 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations