Gene
ccr8.1
- ID
- ZDB-GENE-070302-1
- Name
- chemokine (C-C motif) receptor 8.1
- Symbol
- ccr8.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have C-C chemokine binding activity and C-C chemokine receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to localize to external side of plasma membrane. Orthologous to several human genes including CCR8 (C-C motif chemokine receptor 8).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Liu et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Chemokine receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
---|---|---|---|---|
UniProtKB:H0WFA9
|
395 | |||
UniProtKB:A0A8M9PNM1
|
395 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
ccr8.1-201
(1)
|
Ensembl | 2,597 nt | ||
mRNA |
ccr8.1-202
(1)
|
Ensembl | 1,248 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-11F7 | ||
Contained in | BAC | DKEY-98G19 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_021472953 (1) | 1598 nt | ||
Genomic | GenBank:BX324207 (1) | 187152 nt | ||
Polypeptide | UniProtKB:A0A8M9PNM1 (1) | 395 aa |
- Blaser, B.W., Moore, J.L., Hagedorn, E.J., Li, B., Riquelme, R., Lichtig, A., Yang, S., Zhou, Y., Tamplin, O.J., Binder, V., Zon, L.I. (2017) CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. The Journal of experimental medicine. 214(4):1011
- Nomiyama, H., Osada, N., and Yoshie, O. (2013) Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history. Genes to cells : devoted to molecular & cellular mechanisms. 18(1):1-16
- Liu, Y., Chang, M.X., Wu, S.G., and Nie, P. (2009) Characterization of C-C chemokine receptor subfamily in teleost fish. Molecular immunology. 46(3):498-504
- Devries, M.E., Kelvin, A.A., Xu, L., Ran, L., Robinson, J., and Kelvin, D.J. (2006) Defining the origins and evolution of the chemokine/chemokine receptor system. Journal of immunology (Baltimore, Md. : 1950). 176(1):401-415
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