Gene
dis3l
- ID
- ZDB-GENE-070209-95
- Name
- DIS3 like exosome 3'-5' exoribonuclease
- Symbol
- dis3l Nomenclature History
- Previous Names
-
- zgc:158615
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable 3'-5'-exoribonuclease activity. Predicted to be involved in rRNA catabolic process. Predicted to act upstream of or within RNA phosphodiester bond hydrolysis, exonucleolytic. Predicted to be located in cytoplasm. Predicted to be part of cytoplasmic exosome (RNase complex). Orthologous to human DIS3L (DIS3 like exosome 3'-5' exoribonuclease).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Cabrera-Quio et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR022966 | Ribonuclease II/R, conserved site |
| Domain | IPR001900 | Ribonuclease II/R |
| Domain | IPR033770 | Exosome complex exonuclease RRP44, S1 domain |
| Domain | IPR033771 | Rrp44-like cold shock domain |
| Domain | IPR041505 | Dis3-like cold-shock domain 2 |
| Family | IPR050180 | RNR Ribonuclease |
| Homologous_superfamily | IPR012340 | Nucleic acid-binding, OB-fold |
Domain Details Per Protein
| Protein | Length | Dis3-like cold-shock domain 2 | Exosome complex exonuclease RRP44, S1 domain | Nucleic acid-binding, OB-fold | Ribonuclease II/R | Ribonuclease II/R, conserved site | RNR Ribonuclease | Rrp44-like cold shock domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A2RV18
|
1057 |
Interactions and Pathways
No data available
Plasmids
No data available