Gene

hip1rb

ID

ZDB-GENE-070209-59

Name

huntingtin interacting protein 1 related b

Symbol

hip1rb Nomenclature History

Previous Names

zgc:158784

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable actin filament binding activity; anion binding activity; and clathrin binding activity. Predicted to be involved in several processes, including actin filament organization; activation of cysteine-type endopeptidase activity involved in apoptotic process; and clathrin coat assembly. Predicted to act upstream of or within apoptotic process and regulation of clathrin-dependent endocytosis. Predicted to be located in clathrin-coated pit and cytoplasm. Predicted to be active in clathrin-coated vesicle. Orthologous to human HIP1R (huntingtin interacting protein 1 related).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hip1rb Human Ortholog

No data available

Associated With hip1rb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002558	I/LWEQ domain
Domain	IPR011417	AP180 N-terminal homology (ANTH) domain
Domain	IPR013809	ENTH domain
Domain	IPR032422	Huntingtin-interacting protein 1, clathrin-binding domain
Family	IPR030224	Sla2 family
Homologous_superfamily	IPR008942	ENTH/VHS
Homologous_superfamily	IPR035964	I/LWEQ domain superfamily

Domain Details Per Protein

Protein	Length	AP180 N-terminal homology (ANTH) domain	ENTH domain	ENTH/VHS	Huntingtin-interacting protein 1, clathrin-binding domain	I/LWEQ domain	I/LWEQ domain superfamily	Sla2 family
UniProtKB:A0A0R4IKR8 InterPro	1065

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	hip1rb-201 (1) Ensembl	Ensembl	3,482 nt	Select Tool ZFIN BLAST
mRNA	hip1rb-202 (1) Ensembl	Ensembl	2,749 nt	Select Tool ZFIN BLAST
mRNA	hip1rb-203 (1) Ensembl	Ensembl	714 nt	Select Tool ZFIN BLAST
ncRNA	hip1rb-002 (1) Ensembl	Ensembl	2,749 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations