ZFIN is now using GRCz12tu for Genomic Data
Gene
nrxn3a
- ID
- ZDB-GENE-070206-9
- Name
- neurexin 3a
- Symbol
- nrxn3a Nomenclature History
- Previous Names
-
- nrxn3aa
- nrxn3ab
- im:7144250
- wu:fj54c11
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable neuroligin family protein binding activity and transmembrane signaling receptor activity. Acts upstream of or within regulation of synapse maturation. Predicted to be located in membrane. Predicted to be part of trans-synaptic protein complex. Predicted to be active in presynaptic active zone membrane. Is expressed in hair cell and lateral line. Human ortholog(s) of this gene implicated in alcohol dependence and nicotine dependence. Orthologous to human NRXN3 (neurexin 3).
- Genome Resources
- Note
-
nrxn3a has two isoforms, alpha (2 forms DQ641432 and DQ641433) and beta (DQ641434)
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7144250 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001791 | Laminin G domain |
| Domain | IPR003585 | Neurexin/syndecan/glycophorin C |
| Domain | IPR027789 | Syndecan/Neurexin domain |
| Family | IPR050372 | Neurexin-related cell adhesion and synaptic protein |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
Domain Details Per Protein
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
nrxn3a-204
(1)
|
Ensembl | 2,987 nt | ||
| mRNA |
nrxn3a-201
(1)
|
Ensembl | 3,623 nt | ||
| mRNA |
nrxn3a-202
(1)
|
Ensembl | 2,099 nt | ||
| mRNA |
nrxn3a-203
(1)
|
Ensembl | 2,408 nt | ||
| mRNA |
nrxn3a-208
(1)
|
Ensembl | 4,008 nt | ||
| ncRNA |
nrxn3a-004
(1)
|
Ensembl | 788 nt | ||
| ncRNA |
nrxn3a-005
(1)
|
Ensembl | 776 nt | ||
| ncRNA |
nrxn3a-006
(1)
|
Ensembl | 437 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers