Gene

nrxn3b

ID

ZDB-GENE-070206-10

Name

neurexin 3b

Symbol

nrxn3b Nomenclature History

Previous Names

nrxn3ba
nrxn3bb

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable metal ion binding activity. Predicted to be involved in angiogenesis. Predicted to act upstream of or within cell adhesion. Predicted to be located in membrane. Orthologous to human NRXN3 (neurexin 3).

Genome Resources

Note

nrxn3b has two isoforms, alpha(2 forms, DQ641435 and DQ641436) and beta (DQ641437)

Comparative Information

Expression

All Expression Data

1 figure from Fu et al., 2022

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nrxn3b Human Ortholog

No data available

Associated With nrxn3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000742	EGF-like domain
Domain	IPR001791	Laminin G domain
Domain	IPR003585	Neurexin/syndecan/glycophorin C
Domain	IPR027789	Syndecan/Neurexin domain
Family	IPR050372	Neurexin-related cell adhesion and synaptic protein
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily

Domain Details Per Protein

Protein	Length	Concanavalin A-like lectin/glucanase domain superfamily	EGF-like domain	Laminin G domain	Neurexin-related cell adhesion and synaptic protein	Neurexin/syndecan/glycophorin C	Syndecan/Neurexin domain
UniProtKB:A1XQY3 InterPro	675
UniProtKB:A1XQY1 InterPro	1686

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	nrxn3b-201 (1) Ensembl	Ensembl	4,215 nt	Select Tool ZFIN BLAST
mRNA	nrxn3b-202 (1) Ensembl	Ensembl	5,064 nt	Select Tool ZFIN BLAST
mRNA	nrxn3b-203 (1) Ensembl	Ensembl	3,077 nt	Select Tool ZFIN BLAST
ncRNA	nrxn3b-002 (1) Ensembl	Ensembl	532 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations