ZFIN is now using GRCz12tu for Genomic Data
Gene
nrxn3b
- ID
- ZDB-GENE-070206-10
- Name
- neurexin 3b
- Symbol
- nrxn3b Nomenclature History
- Previous Names
-
- nrxn3ba
- nrxn3bb
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable neuroligin family protein binding activity and transmembrane signaling receptor activity. Acts upstream of or within regulation of synapse maturation. Predicted to be located in membrane. Predicted to be part of trans-synaptic protein complex. Predicted to be active in presynaptic active zone membrane. Is expressed in hair cell and lateral line. Human ortholog(s) of this gene implicated in alcohol dependence and nicotine dependence. Orthologous to human NRXN3 (neurexin 3).
- Genome Resources
- Note
-
nrxn3b has two isoforms, alpha(2 forms, DQ641435 and DQ641436) and beta (DQ641437)
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001791 | Laminin G domain |
| Domain | IPR003585 | Neurexin/syndecan/glycophorin C |
| Domain | IPR027789 | Syndecan/Neurexin domain |
| Family | IPR050372 | Neurexin-related cell adhesion and synaptic protein |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
Domain Details Per Protein
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nrxn3b-201
(1)
|
Ensembl | 4,215 nt | ||
| mRNA |
nrxn3b-202
(1)
|
Ensembl | 5,064 nt | ||
| mRNA |
nrxn3b-203
(1)
|
Ensembl | 3,077 nt | ||
| ncRNA |
nrxn3b-002
(1)
|
Ensembl | 532 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers