Gene

sec24d

ID
ZDB-GENE-070117-2501
Name
SEC24 homolog D, COPII coat complex component
Symbol
sec24d Nomenclature History
Previous Names
  • bul
  • bulldog (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable SNARE binding activity and zinc ion binding activity. Acts upstream of or within cartilage morphogenesis; embryonic viscerocranium morphogenesis; and extracellular matrix constituent secretion. Predicted to be located in cytoplasmic vesicle; cytosol; and endoplasmic reticulum membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Is expressed in several structures, including immature eye; myotome; nervous system; notochord; and pharyngeal arch cartilage. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Orthologous to human SEC24D (SEC24 homolog D, COPII coat complex component).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
14 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sec24d Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cole-Carpenter syndrome Alliance Cole-Carpenter syndrome 2 616294
1 - 1 of 1
Associated With sec24d Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006895 Zinc finger, Sec23/Sec24-type
Domain IPR006896 Sec23/Sec24, trunk domain
Domain IPR006900 Sec23/Sec24, helical domain
Domain IPR007123 Gelsolin-like domain
Domain IPR012990 Sec23/Sec24 beta-sandwich
1 - 5 of 12 Show all
Domain Details Per Protein
Protein Length ADF-H/Gelsolin-like domain superfamily Gelsolin-like domain Gelsolin-like domain superfamily Sec23/Sec24 beta-sandwich SEC23/SEC24 family, SEC24 subfamily Sec23/Sec24, helical domain Sec23/Sec24 helical domain superfamily Sec23/Sec24, trunk domain Sec24-like, trunk domain von Willebrand factor A-like domain superfamily Zinc finger, Sec23/Sec24-type Zinc finger, Sec23/Sec24-type superfamily
UniProtKB:F1QRB4 1030
UniProtKB:D5LMH4 1029
1 - 2 of 2
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sec24d-201 (1) Ensembl 4,532 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations