Gene
eif4g1a
- ID
- ZDB-GENE-070112-702
- Name
- eukaryotic translation initiation factor 4 gamma, 1a
- Symbol
- eif4g1a Nomenclature History
- Previous Names
-
- fb50a05
- wu:fb50a05
- wu:fc60b06
- zgc:158450 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have mRNA binding activity and translation initiation factor activity. Predicted to localize to eukaryotic translation initiation factor 4F complex. Human ortholog(s) of this gene implicated in late onset Parkinson's disease. Orthologous to human EIF4G1 (eukaryotic translation initiation factor 4 gamma 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Babu et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Parkinson disease 18} | 614251 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Armadillo-type fold | Initiation factor eIF-4 gamma, MA3 | MIF4G-like, type 3 | Translation initiation factor eIF4G-like, eIF4E-binding domain | W2 domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A1L1W1
|
1585 | |||||
|
UniProtKB:A0A8M3B020
|
1640 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
eif4g1a-201
(1)
|
Ensembl | 10,021 nt | ||
| mRNA |
eif4g1a-202
(1)
|
Ensembl | 6,454 nt | ||
| mRNA |
eif4g1a-203
(1)
|
Ensembl | 860 nt | ||
| mRNA |
eif4g1a-204
(1)
|
Ensembl | 9,910 nt | ||
| mRNA |
eif4g1a-205
(1)
|
Ensembl | 9,868 nt | ||
| mRNA |
eif4g1a-206
(1)
|
Ensembl | 9,898 nt |
Interactions and Pathways
No data available
Plasmids
No data available