ZFIN is now using GRCz12tu for Genomic Data
Gene
sgo1
- ID
- ZDB-GENE-070112-422
- Name
- shugoshin 1
- Symbol
- sgo1 Nomenclature History
- Previous Names
-
- sgol1 (1)
- zgc:158297
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Acts upstream of or within homeostasis of number of retina cells; regulation of heart contraction; and retinal pigment epithelium development. Predicted to be located in chromosome, centromeric region and nucleus. Predicted to be part of mitotic cohesin complex. Predicted to be active in kinetochore. Is expressed in ciliary marginal zone; heart; and intestine. Human ortholog(s) of this gene implicated in chronic atrial and intestinal dysrhythmia. Orthologous to human SGO1 (shugoshin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| chronic atrial and intestinal dysrhythmia | Alliance | Chronic atrial and intestinal dysrhythmia | 616201 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Shugoshin 1/2 | Shugoshin, C-terminal |
|---|---|---|---|---|
| UniProtKB:A1L1S4 | InterPro | 618 | ||
| UniProtKB:A0A8M9PNJ5 | InterPro | 561 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers