Gene

mogs

ID

ZDB-GENE-070112-412

Name

mannosyl-oligosaccharide glucosidase

Symbol

mogs Nomenclature History

Previous Names

im:7160827
wu:fe50a12
wu:fk09a10
zgc:158312 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to enable Glc3Man9GlcNAc2 oligosaccharide glucosidase activity. Predicted to be involved in protein N-linked glycosylation. Predicted to act upstream of or within oligosaccharide metabolic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIb. Orthologous to human MOGS (mannosyl-oligosaccharide glucosidase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7160827 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mogs Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
congenital disorder of glycosylation type IIb	Alliance	Congenital disorder of glycosylation, type IIb	606056

Associated With mogs Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR031335	Glycosyl hydrolase family 63, C-terminal
Domain	IPR031631	Glycosyl hydrolase family 63, N-terminal
Family	IPR004888	Glycoside hydrolase family 63
Homologous_superfamily	IPR008928	Six-hairpin glycosidase superfamily
Homologous_superfamily	IPR012341	Six-hairpin glycosidase-like superfamily
Homologous_superfamily	IPR038518	Glycosyl hydrolase family 63, N-terminal domain superfamily