ZFIN is now using GRCz12tu for Genomic Data
Gene

galt

ID
ZDB-GENE-070112-172
Name
galactose-1-phosphate uridylyltransferase
Symbol
galt Nomenclature History
Previous Names
  • zgc:158795 (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Enables UDP-glucose:hexose-1-phosphate uridylyltransferase activity. Acts upstream of or within galactose catabolic process via UDP-galactose. Predicted to be active in cytoplasm. Used to study classic galactosemia and galactosemia. Human ortholog(s) of this gene implicated in classic galactosemia. Orthologous to human GALT (galactose-1-phosphate uridylyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With galt Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
classic galactosemia Alliance Galactosemia 230400
Associated With galt Via Experimental Models
Human Disease Fish Conditions Citations
classic galactosemia galtzf2028/zf2028 standard conditions Delnoy et al., 2022
galactosemia galtzf2028/zf2028 standard conditions Vanoevelen et al., 2017
galactosemia galtzf2029/zf2029 standard conditions Vanoevelen et al., 2017
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site
Domain IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal
Domain IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal
Family IPR001937 Galactose-1-phosphate uridyl transferase, class I
Homologous_superfamily IPR036265 HIT-like superfamily
Domain Details Per Protein
Protein Additional Resources Length Galactose-1-phosphate uridyl transferase, class I Galactose-1-phosphate uridyl transferase, class I His-active site Galactose-1-phosphate uridyl transferase, C-terminal Galactose-1-phosphate uridyl transferase, N-terminal HIT-like superfamily
UniProtKB:A0A8M6Z8T3 InterPro 391
UniProtKB:E9QE09 InterPro 364
UniProtKB:A0A8M9QC62 InterPro 187
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA galt-201 (1)
Ensembl
Ensembl 1,417 nt
ZFIN BLAST
mRNA galt-203 (1)
Ensembl
Ensembl 1,857 nt
ZFIN BLAST
ncRNA galt-002 (1)
Ensembl
Ensembl 806 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.