Gene

trpm1a

ID

ZDB-GENE-070112-1372

Name

transient receptor potential cation channel, subfamily M, member 1a

Symbol

trpm1a Nomenclature History

Previous Names

trpm1
trpm1b (1)
zgc:158632 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have cation channel activity. Predicted to be involved in several processes, including G protein-coupled glutamate receptor signaling pathway; cellular response to light stimulus; and protein tetramerization. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in congenital stationary night blindness and congenital stationary night blindness 1C. Is expressed in optic furrow; presumptive retinal pigmented epithelium; retinal inner nuclear layer; and retinal pigmented epithelium. Orthologous to human TRPM1 (transient receptor potential cation channel subfamily M member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trpm1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
congenital stationary night blindness 1C	Alliance	Night blindness, congenital stationary (complete), 1C, autosomal recessive	613216

Associated With trpm1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR005821	Ion transport domain
Domain	IPR032415	TRPM, tetramerisation domain
Domain	IPR041491	TRPM, SLOG domain
Family	IPR050927	Transient receptor potential cation channel M
Homologous_superfamily	IPR037162	TRPM, tetramerisation domain superfamily

Domain Details Per Protein

Protein	Length	Ion transport domain	Transient receptor potential cation channel M	TRPM, SLOG domain	TRPM, tetramerisation domain	TRPM, tetramerisation domain superfamily
UniProtKB:A1L239 InterPro	319
UniProtKB:A0A8M6Z7Q8 InterPro	1647
UniProtKB:A0A8M6YZ91 InterPro	1552
UniProtKB:E7FDL5 InterPro	1546
UniProtKB:A0A8M6Z1K6 InterPro	1653

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	trpm1a-201 (1) Ensembl	Ensembl	5,842 nt	Select Tool
mRNA	trpm1a-202 (1) Ensembl	Ensembl	964 nt	Select Tool ZFIN BLAST
mRNA	trpm1a-203 (1) Ensembl	Ensembl	1,351 nt	Select Tool
mRNA	trpm1a-204 (1) Ensembl	Ensembl	872 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations