Gene

cd226

ID
ZDB-GENE-070112-1322
Name
CD226 molecule
Symbol
cd226 Nomenclature History
Previous Names
  • zgc:158817
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in positive regulation of Fc receptor mediated stimulatory signaling pathway; positive regulation of T cell receptor signaling pathway; and positive regulation of immunoglobulin mediated immune response. Predicted to act upstream of or within positive regulation of natural killer cell cytokine production. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CD226 (CD226 molecule).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa44108Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-cd226
    Keatinge et al., 2021
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    Human Disease
    Associated With cd226 Human Ortholog
    No data available
    Associated With cd226 Via Experimental Models
    No data available
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    Type InterPro ID Name
    Domain IPR003599 Immunoglobulin domain subtype
    Domain IPR007110 Immunoglobulin-like domain
    Domain IPR013106 Immunoglobulin V-set domain
    Family IPR042842 CD226 antigen
    Homologous_superfamily IPR013783 Immunoglobulin-like fold
    1 - 5 of 6 Show all
    Domain Details Per Protein
    Protein Additional Resources Length CD226 antigen Immunoglobulin domain subtype Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin V-set domain
    UniProtKB:A0A8M2B9N9 InterPro 311
    UniProtKB:A1L2D6 InterPro 344
    1 - 2 of 2
    Transcripts
    Genome Browsers
    Genome Build: GRCz11Chromosome: 24
    Type Name Annotation Method Has Havana Data Length (nt) Analysis
    mRNA cd226-201 (1) Ensembl 1,542 nt
    mRNA cd226-202 (1) Ensembl 2,518 nt
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    Interactions and Pathways
    No data available
    Antibodies
    No data available
    Plasmids
    No data available
    Constructs
    No data available
    Marker Relationships
    Relationship Marker Type Marker Accession Numbers Citations
    Contained inBACCH211-277I17ZFIN Curated Data
    Contained inBACDKEY-172H9ZFIN Curated Data
    EncodesESTcssl:d0639Thisse et al., 2008
    EncodescDNAMGC:158817ZFIN Curated Data
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    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanCD22618
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    MouseCd22618
    Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Citations
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