Gene

nefmb

ID
ZDB-GENE-070103-4
Name
neurofilament medium chain b
Symbol
nefmb Nomenclature History
Previous Names
  • nefm (1)
  • zgc:158491 (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have structural molecule activity. Predicted to be involved in neurofilament bundle assembly. Predicted to localize to neurofilament. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is expressed in central nervous system and neurons. Orthologous to human NEFM (neurofilament medium).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Dee et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nefmb Human Ortholog
No data available
Associated With nefmb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018039 Intermediate filament protein, conserved site
Domain IPR039008 Intermediate filament, rod domain
Family IPR002957 Keratin, type I
Family IPR027697 Neurofilament medium polypeptide
Domain Details Per Protein
Protein Length Intermediate filament protein, conserved site Intermediate filament, rod domain Keratin, type I Neurofilament medium polypeptide
UniProtKB:B0S553 717
UniProtKB:A2RUZ3 707
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations