Gene
tmtc3
- ID
- ZDB-GENE-061221-2
- Name
- transmembrane O-mannosyltransferase targeting cadherins 3
- Symbol
- tmtc3 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable mannosyltransferase activity. Predicted to be involved in protein O-linked glycosylation via mannose. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in lissencephaly 8. Orthologous to human TMTC3 (transmembrane O-mannosyltransferase targeting cadherins 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| lissencephaly 8 | Alliance | Lissencephaly 8 | 617255 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein O-mannosyl-transferase TMTC, DUF1736 | Tetratricopeptide-like helical domain superfamily | Tetratricopeptide repeat |
|---|---|---|---|---|---|
| UniProtKB:E7FG92 | InterPro | 932 |
Interactions and Pathways
No data available
Plasmids
No data available