Gene
kcnc1a
- ID
- ZDB-GENE-061220-10
- Name
- potassium voltage-gated channel, Shaw-related subfamily, member 1a
- Symbol
- kcnc1a Nomenclature History
- Previous Names
-
- kcnc1
- zgc:194940
- zgc:194950
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to localize to several cellular components, including dendrite membrane; neuronal cell body membrane; and voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 7. Orthologous to human KCNC1 (potassium voltage-gated channel subfamily C member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Safarian et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| progressive myoclonus epilepsy 7 | Alliance | Epilepsy, progressive myoclonic 7 | 616187 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000210 | BTB/POZ domain |
| Domain | IPR003131 | Potassium channel tetramerisation-type BTB domain |
| Domain | IPR005821 | Ion transport domain |
| Family | IPR003968 | Potassium channel, voltage dependent, Kv |
| Family | IPR003974 | Potassium channel, voltage dependent, Kv3 |
| Homologous_superfamily | IPR011333 | SKP1/BTB/POZ domain superfamily |
| Homologous_superfamily | IPR027359 | Voltage-dependent channel domain superfamily |
Domain Details Per Protein
| Protein | Length | BTB/POZ domain | Ion transport domain | Potassium channel tetramerisation-type BTB domain | Potassium channel, voltage dependent, Kv | Potassium channel, voltage dependent, Kv3 | SKP1/BTB/POZ domain superfamily | Voltage-dependent channel domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:B3DJD2
|
605 | |||||||
|
UniProtKB:E0R7P6
|
584 | |||||||
|
UniProtKB:A0A8M2BG67
|
599 | |||||||
|
UniProtKB:E0R7P5
|
609 | |||||||
|
UniProtKB:A0A8M9PP12
|
606 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kcnc1a-201
(1)
|
Ensembl | 6,573 nt | ||
| mRNA |
kcnc1a-202
(1)
|
Ensembl | 1,755 nt | ||
| mRNA |
kcnc1a-203
(1)
|
Ensembl | 1,830 nt |
Interactions and Pathways
No data available
Plasmids
No data available