Community Action Needed: Please respond to the NIH RFI
Gene

kcnc1a

ID
ZDB-GENE-061220-10
Name
potassium voltage-gated channel, Shaw-related subfamily, member 1a
Symbol
kcnc1a Nomenclature History
Previous Names
  • kcnc1
  • zgc:194940
  • zgc:194950
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to act upstream of or within several processes, including potassium ion transport; protein homooligomerization; and regulation of ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in axon; dendrite membrane; and neuronal cell body membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 7. Orthologous to human KCNC1 (potassium voltage-gated channel subfamily C member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Safarian et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcnc1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
progressive myoclonus epilepsy 7 Alliance Epilepsy, progressive myoclonic 7 616187
Associated With kcnc1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR003131 Potassium channel tetramerisation-type BTB domain
Domain IPR005821 Ion transport domain
Family IPR003968 Potassium channel, voltage dependent, Kv
Family IPR003974 Potassium channel, voltage dependent, Kv3
Family IPR028325 Voltage-gated potassium channel
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Homologous_superfamily IPR027359 Voltage-dependent channel domain superfamily
Domain Details Per Protein
Protein Length BTB/POZ domain Ion transport domain Potassium channel tetramerisation-type BTB domain Potassium channel, voltage dependent, Kv Potassium channel, voltage dependent, Kv3 SKP1/BTB/POZ domain superfamily Voltage-dependent channel domain superfamily Voltage-gated potassium channel
UniProtKB:E0R7P6 584
UniProtKB:E0R7P5 609
UniProtKB:B3DJD2 605
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations