Gene
g6pc3
- ID
- ZDB-GENE-061215-19
- Name
- glucose-6-phosphatase catalytic subunit 3
- Symbol
- g6pc3 Nomenclature History
- Previous Names
-
- zgc:158425
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have glucose-6-phosphatase activity. Predicted to be involved in gluconeogenesis and glucose 6-phosphate metabolic process. Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Human ortholog(s) of this gene implicated in severe congenital neutropenia. Is expressed in ventral wall of dorsal aorta. Orthologous to human G6PC3 (glucose-6-phosphatase catalytic subunit 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhang et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zhang et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| severe congenital neutropenia 4 | Alliance | Dursun syndrome | 612541 |
| severe congenital neutropenia 4 | Alliance | Neutropenia, severe congenital 4, autosomal recessive | 612541 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glucose-6-phosphatase | Phosphatidic acid phosphatase type 2/haloperoxidase | Phosphatidic acid phosphatase type 2/haloperoxidase superfamily |
|---|---|---|---|---|
|
UniProtKB:A1A5Z0
|
339 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available