Gene
trpm4b.2
- ID
- ZDB-GENE-061214-2
- Name
- transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
- Symbol
- trpm4b.2 Nomenclature History
- Previous Names
-
- trpm4b1 (1)
- trpm4c
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable calcium activated cation channel activity. Predicted to act upstream of or within several processes, including cardiac conduction; regulation of T cell cytokine production; and vasoconstriction. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis et progressiva 6 and progressive familial heart block type IB. Orthologous to human TRPM4 (transient receptor potential cation channel subfamily M member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| erythrokeratodermia variabilis et progressiva 6 | Alliance | Erythrokeratodermia variabilis et progressiva 6 | 618531 |
| progressive familial heart block type IB | Alliance | Progressive familial heart block, type IB | 604559 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ion transport domain | Transient receptor potential cation channel M | TRPM, SLOG domain |
|---|---|---|---|---|
|
UniProtKB:F1RC25
|
1222 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
trpm4b.2-201
(1)
|
Ensembl | 3,990 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance