Gene
tmie
- ID
- ZDB-GENE-061207-9
- Name
- transmembrane inner ear
- Symbol
- tmie Nomenclature History
- Previous Names
-
- si:ch211-163f10.1
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Involved in posterior lateral line neuromast primordium migration; sensory organ development; and sensory perception of sound. Predicted to localize to integral component of membrane. Is expressed in brain and otic vesicle. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 6 and sensorineural hearing loss. Orthologous to human TMIE (transmembrane inner ear).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Deafness, autosomal recessive 6 | 600971 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Family | IPR032006 | Transmembrane inner ear expressed protein |
Domain Details Per Protein
Protein | Length | Transmembrane inner ear expressed protein |
---|---|---|
UniProtKB:D2ITC5
|
231 | |
UniProtKB:A2AVI6
|
175 | |
UniProtKB:A0A8M9Q9E3
|
125 |
Interactions and Pathways
No data available
Plasmids
No data available