Gene

exoc1l

ID

ZDB-GENE-061207-63

Name

exocyst complex component 1 like

Symbol

exoc1l Nomenclature History

Previous Names

im:7157987
si:dkey-245p14.4

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Is expressed in neurons; spinal cord; and trigeminal ganglion. Orthologous to human EXOC1L (exocyst complex component 1 like).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7157987 (18 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen
sa24841	Allele with one point mutation	Unknown	Premature Stop	ENU
zko373a	Allele with one deletion	Unknown	Unknown	CRISPR
zko373b	Allele with one deletion	Unknown	Unknown	CRISPR

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Sequence Targeting Reagents

Targeting Reagent	Created Alleles	Citations
CRISPR1-exoc1l	zko373a zko373b	Sun et al., 2019

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Human Disease

Associated With exoc1l Human Ortholog

No data available

Associated With exoc1l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR028258	Exocyst complex component Sec3, PIP2-binding N-terminal domain

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Domain Details Per Protein

Protein	Additional Resources	Length	Exocyst complex component Sec3, PIP2-binding N-terminal domain
UniProtKB:B8A5K8	InterPro	183

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Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 1

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	si:dkey-245p14.4-201 (1) Ensembl	Ensembl		887 nt	Select Tool ZFIN BLAST

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Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	DKEY-245P14	BX548248	ZFIN Curated Data
Encodes	EST	IMAGE:7157987	CK693476	Thisse et al., 2004

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001114848 (1)	887 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX548248 (1)	195620 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:B8A5K8 (1)	183 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	EXOC1L	4	Ensembl:ENSG00000250821 Gene:644145 HGNC:53433	Conserved genome location (synteny) (1) Phylogenetic tree (1) Amino acid sequence comparison (1)
Mouse	Exoc1l	5	Ensembl:ENSMUSG00000091204 Gene:639545 MGI:3647743	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)

Citations

Include unpublished citations

Sun, Y., Zhang, B., Luo, L., Shi, D.L., Wang, H., Cui, Z., Huang, H., Cao, Y., Shu, X., Zhang, W., Zhou, J., Li, Y., Du, J., Zhao, Q., Chen, J., Zhong, H., Zhong, T.P., Li, L., Xiong, J.W., Peng, J., Xiao, W., Zhang, J., Yao, J., Yin, Z., Mo, X., Peng, G., Zhu, J., Chen, Y., Zhou, Y., Liu, D., Pan, W., Zhang, Y., Ruan, H., Liu, F., Zhu, Z., Meng, A., ZAKOC Consortium (2019) Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9. Genome research. 30(1):118-26

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