Gene

p3h2

ID
ZDB-GENE-061207-44
Name
prolyl 3-hydroxylase 2
Symbol
p3h2 Nomenclature History
Previous Names
  • leprel1
  • si:ch211-117l17.2
  • si:ch211-87n12.2
  • si:dkey-193b19.1
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to enable procollagen-proline 3-dioxygenase activity. Predicted to be involved in collagen metabolic process. Predicted to be active in endoplasmic reticulum. Orthologous to human P3H2 (prolyl 3-hydroxylase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa43842Allele with one point mutationUnknownSplice SiteENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
sa44988Allele with one point mutationUnknownUnknownENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
1 - 2 of 2
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Sequence Targeting Reagents
No data available
Human Disease
Associated With p3h2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Myopia, high, with cataract and vitreoretinal degeneration 614292
1 - 1 of 1
Associated With p3h2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005123 Oxoglutarate/iron-dependent dioxygenase domain
Domain IPR006620 Prolyl 4-hydroxylase, alpha subunit
Domain IPR044862 Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain
Family IPR039575 Prolyl 3-hydroxylase
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
1 - 5 of 5
Domain Details Per Protein
Protein Additional Resources Length Oxoglutarate/iron-dependent dioxygenase domain Prolyl 3-hydroxylase Prolyl 4-hydroxylase, alpha subunit Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain Tetratricopeptide-like helical domain superfamily
UniProtKB:A0A8M9Q9Y5 InterPro 678
UniProtKB:A0A0R4IJJ1 InterPro 678
1 - 2 of 2
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 22
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA p3h2-201 (1)
Ensembl
Ensembl 5,845 nt
ZFIN BLAST
mRNA p3h2-202 (1)
Ensembl
Ensembl 3,824 nt
ZFIN BLAST
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-87N12ZFIN Curated Data
Contained inBACCH211-117L17ZFIN Curated Data
Contained inBACDKEY-193B19ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_003201065 (1)
ZFIN BLASTNCBI BLASTMegaBLASTEnsemblUCSC BLAT
GenomicGenBank:BX649608 (1)169649 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:A0A0R4IJJ1 (1)678 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanP3H23
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
No data available
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