Gene
p3h2
- ID
- ZDB-GENE-061207-44
- Name
- prolyl 3-hydroxylase 2
- Symbol
- p3h2 Nomenclature History
- Previous Names
-
- leprel1
- si:ch211-117l17.2
- si:ch211-87n12.2
- si:dkey-193b19.1
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have procollagen-proline 3-dioxygenase activity. Predicted to be involved in collagen metabolic process. Predicted to localize to endoplasmic reticulum. Orthologous to human P3H2 (prolyl 3-hydroxylase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Myopia, high, with cataract and vitreoretinal degeneration | 614292 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005123 | Oxoglutarate/iron-dependent dioxygenase domain |
| Domain | IPR006620 | Prolyl 4-hydroxylase, alpha subunit |
| Domain | IPR044862 | Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain |
| Family | IPR039575 | Prolyl 3-hydroxylase |
| Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
Domain Details Per Protein
| Protein | Length | Oxoglutarate/iron-dependent dioxygenase domain | Prolyl 3-hydroxylase | Prolyl 4-hydroxylase, alpha subunit | Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain | Tetratricopeptide-like helical domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q9Y5
|
678 | |||||
|
UniProtKB:A0A0R4IJJ1
|
678 |
Interactions and Pathways
No data available
Plasmids
No data available