Gene

nav2b

ID

ZDB-GENE-061207-13

Name

neuron navigator 2b

Symbol

nav2b Nomenclature History

Previous Names

im:7155999
im:7156396
si:ch211-169k21.2

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in nervous system development. Predicted to act upstream of or within neurogenesis. Is expressed in several structures, including anterior axial hypoblast; brain; immature eye; midbrain hindbrain boundary neural keel; and midbrain neural rod. Orthologous to human NAV2 (neuron navigator 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7156396 (18 images)
IMAGE:7155999 (22 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nav2b Human Ortholog

No data available

Associated With nav2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001715	Calponin homology domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR003959	ATPase, AAA-type, core
Family	IPR039041	Nav/unc-53 family
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036872	CH domain superfamily

Domain Details Per Protein

Protein	Length	AAA+ ATPase domain	ATPase, AAA-type, core	Calponin homology domain	CH domain superfamily	Nav/unc-53 family	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M3B755 InterPro	2255
UniProtKB:A0A8M9P6R8 InterPro	1793
UniProtKB:A0A8M9PN60 InterPro	2251
UniProtKB:A0A8M9PYW9 InterPro	1375
UniProtKB:A0A8M9PVF5 InterPro	2240
UniProtKB:A0A8M9PH94 InterPro	1485
UniProtKB:A0A8M9P6R4 InterPro	2275
UniProtKB:A0A8M9Q5D3 InterPro	2278
UniProtKB:A0A8M9PVE8 InterPro	2278
UniProtKB:A0A8M9PZ87 InterPro	1375
UniProtKB:A0A8M9PN65 InterPro	1471
UniProtKB:A0A8M9PT96 InterPro	1471
UniProtKB:A0A8M9PG77 InterPro	1485
UniProtKB:A0A8M9PYW5 InterPro	2248
UniProtKB:A0A8M9PH89 InterPro	2256

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	nav2b-202 (1) Ensembl	Ensembl		8,181 nt	Select Tool ZFIN BLAST
ncRNA	nav2b-002 (1) Ensembl	Ensembl		139 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations