Gene
olfcn1
- ID
- ZDB-GENE-061117-2
- Name
- olfactory receptor C family, n1
- Symbol
- olfcn1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in olfactory epithelium.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Ahuja et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa2984 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa10950 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa13020 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa14843 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa36681 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017979 | GPCR, family 3, conserved site |
| Domain | IPR001828 | Receptor, ligand binding region |
| Domain | IPR011500 | GPCR, family 3, nine cysteines domain |
| Domain | IPR017978 | GPCR family 3, C-terminal |
| Family | IPR000068 | GPCR, family 3, extracellular calcium-sensing receptor-related |
| Family | IPR000337 | GPCR, family 3 |
| Family | IPR004073 | GPCR, family 3, vomeronasal receptor, type 2 |
| Homologous_superfamily | IPR028082 | Periplasmic binding protein-like I |
| Homologous_superfamily | IPR038550 | GPCR, family 3, nine cysteines domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, family 3 | GPCR, family 3, conserved site | GPCR family 3, C-terminal | GPCR, family 3, extracellular calcium-sensing receptor-related | GPCR, family 3, nine cysteines domain | GPCR, family 3, nine cysteines domain superfamily | GPCR, family 3, vomeronasal receptor, type 2 | Periplasmic binding protein-like I | Receptor, ligand binding region |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1RA84 | InterPro | 855 | |||||||||
| UniProtKB:A0AB40ECF2 | InterPro | 752 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fp016180.1-202
(1)
|
Ensembl | 4,525 nt | ||
| mRNA |
si:ch73-125k17.2-202
(1)
|
Ensembl | 1,295 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-125K17 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_009293708 (1) | |||
| Genomic | GenBank:FP016180 | 99694 nt | ||
| Polypeptide | UniProtKB:F1RA84 (1) | 855 aa |
No data available
- Yang, L., Jiang, H., Wang, Y., Lei, Y., Chen, J., Sun, N., Lv, W., Wang, C., Near, T.J., He, S. (2019) Expansion of vomeronasal receptor genes (OlfC) in the evolution of fright reaction in Ostariophysan fishes. Communications biology. 2:235
- Ahuja, G., Reichel, V., Kowatschew, D., Syed, A.S., Kotagiri, A.K., Oka, Y., Weth, F., Korsching, S.I. (2018) Overlapping but distinct topology for zebrafish V2R-like olfactory receptors reminiscent of odorant receptor spatial expression zones. BMC Genomics. 19:383
- Saraiva, L.R., Ahuja, G., Ivandic, I., Syed, A.S., Marioni, J.C., Korsching, S.I., Logan, D.W. (2015) Molecular and neuronal homology between the olfactory systems of zebrafish and mouse. Scientific Reports. 5:11487
- Alioto, T.S., and Ngai, J. (2006) The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids. BMC Genomics. 7(1):309
- Hashiguchi, Y., and Nishida, M. (2006) Evolution and origin of vomeronasal-type odorant receptor gene repertoire in fishes. BMC Evolutionary Biology. 6:76
- Hashiguchi, Y., and Nishida, M. (2005) Evolution of vomeronasal-type odorant receptor genes in the zebrafish genome. Gene. 362C:19-28
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