Gene

kcnh5a

ID

ZDB-GENE-061106-2

Name

potassium voltage-gated channel, subfamily H (eag-related), member 5a

Symbol

kcnh5a Nomenclature History

Previous Names

kcnh5

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport and regulation of membrane potential. Predicted to act upstream of or within potassium ion transport; regulation of monoatomic ion transmembrane transport; and transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human KCNH5 (potassium voltage-gated channel subfamily H member 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kcnh5a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Developmental and epileptic encephalopathy 112	620537

Associated With kcnh5a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000014	PAS domain
Domain	IPR000595	Cyclic nucleotide-binding domain
Domain	IPR000700	PAS-associated, C-terminal
Domain	IPR005821	Ion transport domain
Family	IPR003949	Potassium channel, voltage-dependent, EAG
Homologous_superfamily	IPR014710	RmlC-like jelly roll fold
Homologous_superfamily	IPR018490	Cyclic nucleotide-binding domain superfamily
Homologous_superfamily	IPR035965	PAS domain superfamily
Repeat	IPR001610	PAC motif