Gene

tmprss4a

ID
ZDB-GENE-061103-631
Name
transmembrane serine protease 4a
Symbol
tmprss4a Nomenclature History
Previous Names
  • tmprss4 (1)
  • zgc:152909
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Is predicted to enable scavenger receptor activity and serine-type endopeptidase activity. Acts upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including gill; heart; integument; liver; and pleuroperitoneal region. Orthologous to human TMPRSS4 (transmembrane serine protease 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Ohler et al., 2011
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Ohler et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tmprss4a Human Ortholog
No data available
Associated With tmprss4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018114 Serine proteases, trypsin family, histidine active site
Active_site IPR033116 Serine proteases, trypsin family, serine active site
Domain IPR001190 SRCR domain
Domain IPR001254 Serine proteases, trypsin domain
Domain IPR017448 SRCR-like domain
Family IPR001314 Peptidase S1A, chymotrypsin family
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR036055 LDL receptor-like superfamily
Homologous_superfamily IPR036772 SRCR-like domain superfamily
Homologous_superfamily IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
Repeat IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
Domain Details Per Protein
Protein Length LDL receptor-like superfamily Low-density lipoprotein (LDL) receptor class A repeat Peptidase S1A, chymotrypsin family Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain Serine proteases, trypsin family, histidine active site Serine proteases, trypsin family, serine active site SRCR domain SRCR-like domain SRCR-like domain superfamily
UniProtKB:A0A0R4IJV1 309
UniProtKB:A0A0R4IB12 154
UniProtKB:A0A0R4ID97 430
UniProtKB:A0JMD5 430
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations