Gene
erbin
- ID
- ZDB-GENE-061103-403
- Name
- erbb2 interacting protein
- Symbol
- erbin Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable protein kinase binding activity. Predicted to be involved in cell-cell adhesion; establishment or maintenance of epithelial cell apical/basal polarity; and protein localization to membrane. Predicted to be active in adherens junction; basolateral plasma membrane; and postsynaptic density. Predicted to colocalize with postsynaptic membrane. Is expressed in intestine. Orthologous to human ERBIN (erbb2 interacting protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001478 | PDZ domain |
| Family | IPR050614 | Synaptic Scaffolding LAP/MAGUK Families |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Repeat | IPR001611 | Leucine-rich repeat |
| Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
Domain Details Per Protein
| Protein | Additional Resources | Length | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype | PDZ domain | PDZ superfamily | Synaptic Scaffolding LAP/MAGUK Families |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B2B1 | InterPro | 1359 | ||||||
| UniProtKB:A0A8M2B233 | InterPro | 1392 | ||||||
| UniProtKB:A0A0R4IEU0 | InterPro | 1330 | ||||||
| UniProtKB:E7EYJ7 | InterPro | 1382 | ||||||
| UniProtKB:A0AB32TYI2 | InterPro | 1349 | ||||||
| UniProtKB:A0AB32U2E6 | InterPro | 643 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
erbin-201
(1)
|
Ensembl | 4,165 nt | ||
| mRNA |
erbin-203
(1)
|
Ensembl | 4,916 nt | ||
| mRNA |
erbin-204
(1)
|
Ensembl | 4,714 nt | ||
| mRNA |
erbin-205
(1)
|
Ensembl | 7,498 nt | ||
| mRNA |
erbin-206
(1)
|
Ensembl | 3,751 nt | ||
| mRNA |
erbin-207
(1)
|
Ensembl | 2,201 nt | ||
| ncRNA |
erbb2ip-003
(1)
|
Ensembl | 679 nt |
Interactions and Pathways
No data available
Plasmids
No data available