Gene
agap2
- ID
- ZDB-GENE-061103-343
- Name
- ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
- Symbol
- agap2 Nomenclature History
- Previous Names
-
- lnc.punisher (1)
- zgc:153779
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have several functions, including GTP binding activity; GTPase activator activity; and GTPase activity. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human AGAP2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Kurian et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Kurian et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001164 | Arf GTPase activating protein |
| Domain | IPR001849 | Pleckstrin homology domain |
| Family | IPR001806 | Small GTPase |
| Family | IPR051282 | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Homologous_superfamily | IPR037278 | ARFGAP/RecO-like zinc finger |
| Homologous_superfamily | IPR038508 | ArfGAP domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | ArfGAP domain superfamily | ARFGAP/RecO-like zinc finger | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein | Arf GTPase activating protein | PH-like domain superfamily | Pleckstrin homology domain | P-loop containing nucleoside triphosphate hydrolase | Small GTPase |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AVN4
|
1082 | ||||||||||
|
UniProtKB:A0A8M3AN70
|
847 | ||||||||||
|
UniProtKB:A0JMI1
|
827 | ||||||||||
|
UniProtKB:A0A8M3AYQ6
|
1110 | ||||||||||
|
UniProtKB:A0A8M3ANW4
|
1130 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available