Gene
agap2
- ID
- ZDB-GENE-061103-343
- Name
- ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
- Symbol
- agap2 Nomenclature History
- Previous Names
-
- lnc.punisher (1)
- zgc:153779
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity and GTPase activity. Acts upstream of or within with a positive effect on heart development and vasculature development. Predicted to be active in cytoplasm; membrane; and nucleus. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human AGAP2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Kurian et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Kurian et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001164 | Arf GTPase activating protein |
| Domain | IPR001849 | Pleckstrin homology domain |
| Family | IPR001806 | Small GTPase |
| Family | IPR051282 | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Homologous_superfamily | IPR037278 | ARFGAP/RecO-like zinc finger |
| Homologous_superfamily | IPR038508 | ArfGAP domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | ArfGAP domain superfamily | ARFGAP/RecO-like zinc finger | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein | Arf GTPase activating protein | PH-like domain superfamily | Pleckstrin homology domain | P-loop containing nucleoside triphosphate hydrolase | Small GTPase |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AVN4 | InterPro | 1082 | ||||||||||
| UniProtKB:A0A8M3AN70 | InterPro | 847 | ||||||||||
| UniProtKB:A0JMI1 | InterPro | 827 | ||||||||||
| UniProtKB:A0A8M3AYQ6 | InterPro | 1110 | ||||||||||
| UniProtKB:A0A8M3ANW4 | InterPro | 1130 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available