header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-061103-307
Gene Name: angiomotin like 2b
Gene Symbol: amotl2b    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:154007

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Involved in actin cytoskeleton organization; dorsal aorta morphogenesis; and regulation of cell shape. Predicted to localize to the bicellular tight junction and cytoplasmic vesicle. Is expressed in ectoderm. Orthologous to human AMOTL2 (angiomotin like 2).
Genome Resources: Alliance (1),  Gene:559784 (1),  Ensembl(GRCz11):ENSDARG00000061948 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Segmentation:14-19 somites (16.0h-19.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32905 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-amotl2b N/A 3
    MO2-amotl2b N/A 1
    MO3-amotl2b N/A 1
    DISEASE ASSOCIATED WITH amotl2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH amotl2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin cytoskeleton organization (more)
    Cellular Component bicellular tight junction (more)
    Molecular Function molecular_function (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR009114 (1)
  • InterPro:IPR024646 (1)
  • Pfam:PF12240 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA amotl2b-201 (1)    Ensembl 2985
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM amotl2b No data available
    MARKER RELATIONSHIPS
    amotl2b Contained in: [BAC] DKEY-261L2 (1) (order this)
    amotl2b Encodes: [cDNA] MGC:154007 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077606 (1) 2993 bp
    Genomic GenBank:BX649390 (1) 184594 bp
    Select Tool
    Polypeptide UniProtKB:B8A5S6 (1) 681 aa
    Sequence Clusters UniGene:42522 (1)
    Sequence Information (all 12)
    ORTHOLOGY for amotl2b ( Chr: 2 )
    CITATIONS (21)