Gene
sfrp1b
- ID
- ZDB-GENE-061103-1
- Name
- secreted frizzled-related protein 1b
- Symbol
- sfrp1b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have Wnt-protein binding activity. Predicted to be involved in canonical Wnt signaling pathway; negative regulation of canonical Wnt signaling pathway; and non-canonical Wnt signaling pathway. Predicted to localize to extracellular space. Is expressed in several structures, including endoderm; pronephric duct; tail bud; yolk; and yolk syncytial layer. Orthologous to human SFRP1 (secreted frizzled related protein 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001134 | Netrin domain |
Domain | IPR018933 | Netrin module, non-TIMP type |
Domain | IPR020067 | Frizzled domain |
Domain | IPR041760 | SFRP1, cysteine-rich domain |
Family | IPR015526 | Frizzled/secreted frizzled-related protein |
Homologous_superfamily | IPR008993 | Tissue inhibitor of metalloproteinases-like, OB-fold |
Homologous_superfamily | IPR036790 | Frizzled cysteine-rich domain superfamily |
Domain Details Per Protein
Protein | Length | Frizzled cysteine-rich domain superfamily | Frizzled domain | Frizzled/secreted frizzled-related protein | Netrin domain | Netrin module, non-TIMP type | SFRP1, cysteine-rich domain | Tissue inhibitor of metalloproteinases-like, OB-fold |
---|---|---|---|---|---|---|---|---|
UniProtKB:A3KNP6
|
300 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
sfrp1b-201
(1)
|
Ensembl | 1,527 nt |
Interactions and Pathways
No data available
Plasmids
No data available