Gene
il17a/f2
- ID
- ZDB-GENE-061031-2
- Name
- interleukin 17a/f2
- Symbol
- il17a/f2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable cytokine activity. Predicted to be located in extracellular region. Is expressed in gill; intestine; and kidney.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa42882 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cystine-knot cytokine | Interleukin-17 family |
|---|---|---|---|---|
| UniProtKB:Q5TKT3 | InterPro | 140 | ||
| UniProtKB:A0A8M3AIQ6 | InterPro | 131 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
il17a/f2-201
(1)
|
Ensembl | 882 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-176M20 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001020798 (1) | |||
| Genomic | GenBank:BX294375 (1) | 188455 nt | ||
| Polypeptide | UniProtKB:Q5TKT3 (1) | 140 aa |
No data available
- Pharkjaksu, S., Boonmee, N., Mitrpant, C., Ngamskulrungroj, P. (2021) Immunopathogenesis of Emerging Candida auris and Candida haemulonii Strains. Journal of fungi (Basel, Switzerland). 7(9):
- Ikeda-Ohtsubo, W., López Nadal, A., Zaccaria, E., Iha, M., Kitazawa, H., Kleerebezem, M., Brugman, S. (2020) Intestinal Microbiota and Immune Modulation in Zebrafish by Fucoidan From Okinawa Mozuku (Cladosiphon okamuranus). Frontiers in nutrition. 7:67
- Nayak, S., Al Ashhab, A., Zilberg, D., Khozin-Goldberg, I. (2020) Dietary Supplementation with Omega-6 LC-PUFA-Rich Microalgae Regulates Mucosal Immune Response and Promotes Microbial Diversity in the Zebrafish Gut. Biology. 9(6):
- Jensen, H.M., Korbut, R., Kania, P.W., Buchmann, K. (2018) Cannabidiol effects on behaviour and immune gene expression in zebrafish (Danio rerio). PLoS One. 13:e0200016
- Bergeron, A.C., Seman, B.G., Hammond, J.H., Archambault, L.S., Hogan, D.A., Wheeler, R.T. (2017) Candida and Pseudomonas interact to enhance virulence of mucosal infection in transparent zebrafish.. Infection and Immunity. 85(11)
- Haarder, S., Kania, P.W., Holm, T.L., von Gersdorff Jørgensen, L., Buchmann, K. (2017) Effect of ES-products from Anisakis (Nematoda: Anisakidae) on experimentally induced colitis in adult zebrafish. Parasite immunology. 39(10)
- Mehrdana, F., Kania, P.W., Nazemi, S., Buchmann, K. (2017) Immunomodulatory effects of excretory/secretory compounds from Contracaecum osculatum larvae in a zebrafish inflammation model. PLoS One. 12:e0181277
- Tokunaga, Y., Shirouzu, M., Sugahara, R., Yoshiura, Y., Kiryu, I., Ototake, M., Nagasawa, T., Somamoto, T., Nakao, M. (2017) Comprehensive validation of T- and B-cell deficiency in rag1-null zebrafish: Implication for the robust innate defense mechanisms of teleosts. Scientific Reports. 7:7536
- Zhang, B., Shimada, Y., Hirota, T., Ariyoshi, M., Kuroyanagi, J., Nishimura, Y., Tanaka, T. (2016) Novel immunologic tolerance of human cancer cell xenotransplants in zebrafish. Translational research : the journal of laboratory and clinical medicine. 170:89-98.e3
- Yoon, S., Mitra, S., Wyse, C., Alnabulsi, A., Zou, J., Weerdenburg, E.M., van der Sar, A.M., Wang, D., Secombes, C.J., Bird, S. (2015) First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio). PLoS One. 10:e0126378
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