Gene
ces2a
- ID
- ZDB-GENE-061013-99
- Name
- carboxylesterase 2a
- Symbol
- ces2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable carboxylic ester hydrolase activity. Is expressed in liver; pectoral fin; pleuroperitoneal region; yolk; and yolk syncytial layer. Human ortholog(s) of this gene implicated in colorectal cancer and gastrointestinal system cancer. Orthologous to several human genes including CES2 (carboxylesterase 2).
- Genome Resources
- Note
-
Some publications were mistakingly attributed to "ces2" before it was determined that there are 2 genes, ces2a and ces2b in zebrafish. The attributions have been corrected. IMPORTANT: qPCR primers for ces2 from Zhao et al. (2010) do not BLAST to any known ces2 sequences
- Comparative Information
-
- All Expression Data
- 11 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6908784 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha/Beta hydrolase fold | Carboxylesterase, type B | Carboxylesterase type B, active site | Carboxylesterase type B, conserved site | Type-B Carboxylesterase/Lipase |
|---|---|---|---|---|---|---|---|
| UniProtKB:F1R9X5 | InterPro | 556 | |||||
| UniProtKB:A0A8M9PPJ2 | InterPro | 554 | |||||
| UniProtKB:A0A8M9PFI2 | InterPro | 419 | |||||
| UniProtKB:Q08BF1 | InterPro | 555 |
Interactions and Pathways
No data available
Plasmids
No data available