ZFIN is now using GRCz12tu for Genomic Data
Gene
odad3
- ID
- ZDB-GENE-061013-787
- Name
- outer dynein arm docking complex subunit 3
- Symbol
- odad3 Nomenclature History
- Previous Names
-
- ccdc151
- flanders
- unm ts272
- unm_ts272
- zgc:152917
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Involved in axonemal dynein complex assembly; cilium movement; and determination of left/right symmetry. Acts upstream of or within several processes, including Kupffer's vesicle development; determination of left/right symmetry; and microtubule cytoskeleton organization. Located in ciliary basal body and motile cilium. Is expressed in several structures, including Kupffer's vesicle; forerunner cell group; intermediate mesoderm; nervous system; and pronephros. Used to study idiopathic scoliosis and primary ciliary dyskinesia. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 30. Orthologous to human ODAD3 (outer dynein arm docking complex subunit 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 30 | Alliance | Ciliary dyskinesia, primary, 30 | 616037 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| idiopathic scoliosis | odad3ts272/ts272 | standard conditions | Rose et al., 2020 |
| primary ciliary dyskinesia | odad3ts272/ts272 | standard conditions | Song et al., 2016 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | ODAD1, central coiled coil region | Outer dynein arm-docking complex subunit 3 |
|---|---|---|---|---|
| UniProtKB:F1QFD6 | InterPro | 545 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ccdc151-201
(1)
|
Ensembl | 1,846 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers