ZFIN is now using GRCz12tu for Genomic Data
Gene
soat2
- ID
- ZDB-GENE-061013-742
- Name
- sterol O-acyltransferase 2
- Symbol
- soat2 Nomenclature History
- Previous Names
-
- ACAT-2 (1)
- zgc:153102
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables cholesterol O-acyltransferase activity. Predicted to be involved in cholesterol efflux and cholesterol metabolic process. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including hatching gland; liver; pleuroperitoneal region; retina; and yolk syncytial layer. Human ortholog(s) of this gene implicated in coronary artery disease and hepatocellular carcinoma. Orthologous to human SOAT2 (sterol O-acyltransferase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Chang et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chang et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Membrane bound O-acyl transferase, MBOAT | Sterol O-acyltransferase, ACAT/DAG/ARE types |
|---|---|---|---|---|
| UniProtKB:A0A8M6YZK6 | InterPro | 534 | ||
| UniProtKB:A0AB13A9C6 | InterPro | 534 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers