Gene
nt5c2b
- ID
- ZDB-GENE-061013-522
- Name
- 5'-nucleotidase, cytosolic IIb
- Symbol
- nt5c2b Nomenclature History
- Previous Names
-
- im:7162273
- zgc:153651
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable 5'-nucleotidase activity. Predicted to be involved in GMP metabolic process. Predicted to act upstream of or within nucleotide metabolic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7162273 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Vishnolia et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 45 | Alliance | Spastic paraplegia 45, autosomal recessive | 613162 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | HAD-like superfamily | HAD superfamily | HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase | Purine 5'-nucleotidase |
|---|---|---|---|---|---|
|
UniProtKB:F1QAK5
|
562 | ||||
|
UniProtKB:A0A8M9PH62
|
564 | ||||
|
UniProtKB:A0A8M9PUC7
|
370 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nt5c2b-201
(1)
|
Ensembl | 1,982 nt | ||
| ncRNA |
nt5c2b-002
(1)
|
Ensembl | 2,295 nt | ||
| ncRNA |
nt5c2b-003
(1)
|
Ensembl | 2,148 nt | ||
| ncRNA |
nt5c2b-004
(1)
|
Ensembl | 716 nt |
Interactions and Pathways
No data available
Plasmids
No data available