Gene
lrrc8da
- ID
- ZDB-GENE-061009-26
- Name
- leucine rich repeat containing 8 VRAC subunit Da
- Symbol
- lrrc8da Nomenclature History
- Previous Names
-
- im:7140212
- si:ch211-83f14.3
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable volume-sensitive anion channel activity. Predicted to be involved in aspartate transmembrane transport; intracellular signal transduction; and monoatomic anion transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including axis; pancreatic bud; polster; ventral mesenchyme; and yolk syncytial layer. Orthologous to human LRRC8D (leucine rich repeat containing 8 VRAC subunit D).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7140212 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Leucine-rich repeat | Leucine-rich repeat domain-containing protein | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype | LRRC8, pannexin-like TM region |
|---|---|---|---|---|---|---|---|
| UniProtKB:A2BIH6 | InterPro | 825 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lrrc8da-201
(1)
|
Ensembl | 2,478 nt | ||
| mRNA |
lrrc8da-202
(1)
|
Ensembl | 5,389 nt |
Interactions and Pathways
No data available
Plasmids
No data available