ZFIN is now using GRCz12tu for Genomic Data
Gene
cyp3c4
- ID
- ZDB-GENE-060929-96
- Name
- cytochrome P450, family 3, subfamily C, polypeptide 4
- Symbol
- cyp3c4 Nomenclature History
- Previous Names
-
- zgc:153269
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable steroid hydroxylase activity. Predicted to be located in membrane. Is expressed in gill; heart; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; and essential hypertension. Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytochrome P450 | Cytochrome P450 3A | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q08CC5 | InterPro | 507 | |||||
| UniProtKB:A0AB32TDY9 | InterPro | 466 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp3c4-201
(1)
|
Ensembl | 2,309 nt | ||
| mRNA |
cyp3c4-202
(1)
|
Ensembl | 2,292 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers