Gene

srd5a1

ID
ZDB-GENE-060929-938
Name
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Symbol
srd5a1 Nomenclature History
Previous Names
  • zgc:153768
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in steroid biosynthetic process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in prostate cancer and prostatic hypertrophy. Orthologous to human SRD5A1 (steroid 5 alpha-reductase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With srd5a1 Human Ortholog
No data available
Associated With srd5a1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001104 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
Family IPR016636 3-oxo-5-alpha-steroid 4-dehydrogenase
Family IPR039357 3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase
Domain Details Per Protein
Protein Length 3-oxo-5-alpha-steroid 4-dehydrogenase 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal 3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase
UniProtKB:Q08C19 265
UniProtKB:A5PMI4 265
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA srd5a1-201 (1) Ensembl 1,770 nt
mRNA srd5a1-202 (1) Ensembl 929 nt
mRNA srd5a1-203 (1) Ensembl 890 nt
ncRNA srd5a1-002 (1) Ensembl 929 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations