Gene
srd5a1
- ID
- ZDB-GENE-060929-938
- Name
- steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
- Symbol
- srd5a1 Nomenclature History
- Previous Names
-
- zgc:153768
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in steroid biosynthetic process. Predicted to act upstream of or within cell differentiation; sex differentiation; and steroid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in prostate cancer and prostatic hypertrophy. Orthologous to human SRD5A1 (steroid 5 alpha-reductase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 3-oxo-5-alpha-steroid 4-dehydrogenase | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal | 3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase |
|---|---|---|---|---|
|
UniProtKB:Q08C19
|
265 | |||
|
UniProtKB:A5PMI4
|
265 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
srd5a1-201
(1)
|
Ensembl | 1,770 nt | ||
| mRNA |
srd5a1-202
(1)
|
Ensembl | 929 nt | ||
| mRNA |
srd5a1-203
(1)
|
Ensembl | 890 nt | ||
| ncRNA |
srd5a1-002
(1)
|
Ensembl | 929 nt |
Interactions and Pathways
No data available
Plasmids
No data available