Gene
mief2
- ID
- ZDB-GENE-060929-864
- Name
- mitochondrial elongation factor 2
- Symbol
- mief2 Nomenclature History
- Previous Names
-
- im:7149098
- smcr7 (1)
- smcr7b
- zgc:152920
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to be involved in positive regulation of mitochondrial fission. Predicted to be active in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 49. Orthologous to human MIEF2 (mitochondrial elongation factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7149098 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined oxidative phosphorylation deficiency 49 | Alliance | ?Combined oxidative phosphorylation deficiency 49 | 619024 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | MAB21L/Cyclic GMP-AMP synthase-like receptor | Mab-21-like, HhH/H2TH-like domain | Mitochondrial dynamics protein MID49/MID51 | Mitochondrial dynamics protein MID51-like, C-terminal domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M1NB06
|
467 |
Interactions and Pathways
No data available
Plasmids
No data available