fdx2

ID

ZDB-GENE-060929-1046

Name

ferredoxin 2

Symbol

fdx2 Nomenclature History

Previous Names

fdx1l
zgc:153554

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable electron transfer activity. Predicted to be involved in [2Fe-2S] cluster assembly and electron transport chain. Predicted to act upstream of with a positive effect on ubiquinone biosynthetic process. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Orthologous to human FDX2 (ferredoxin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fdx2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
mitochondrial myopathy	Alliance	Mitochondrial myopathy, episodic, with optic atrophy and reversible leukoencephalopathy	251900

Associated With fdx2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018298	Adrenodoxin, iron-sulphur binding site
Domain	IPR001041	2Fe-2S ferredoxin-type iron-sulfur binding domain
Family	IPR001055	Adrenodoxin-like
Homologous_superfamily	IPR012675	Beta-grasp domain superfamily
Homologous_superfamily	IPR036010	2Fe-2S ferredoxin-like superfamily