Gene
fdx2
- ID
- ZDB-GENE-060929-1046
- Name
- ferredoxin 2
- Symbol
- fdx2 Nomenclature History
- Previous Names
-
- fdx1l
- zgc:153554
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have 2 iron, 2 sulfur cluster binding activity; electron transfer activity; and metal ion binding activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to mitochondrial matrix. Human ortholog(s) of this gene implicated in mitochondrial myopathy. Orthologous to human FDX2 (ferredoxin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial myopathy | Alliance | Mitochondrial myopathy, episodic, with optic atrophy and reversible leukoencephalopathy | 251900 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018298 | Adrenodoxin, iron-sulphur binding site |
| Domain | IPR001041 | 2Fe-2S ferredoxin-type iron-sulfur binding domain |
| Family | IPR001055 | Adrenodoxin-like |
| Homologous_superfamily | IPR012675 | Beta-grasp domain superfamily |
| Homologous_superfamily | IPR036010 | 2Fe-2S ferredoxin-like superfamily |
Domain Details Per Protein
| Protein | Length | 2Fe-2S ferredoxin-like superfamily | 2Fe-2S ferredoxin-type iron-sulfur binding domain | Adrenodoxin, iron-sulphur binding site | Adrenodoxin-like | Beta-grasp domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q08C57
|
195 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available