Gene

uhmk1

ID

ZDB-GENE-060929-1014

Name

U2AF homology motif (UHM) kinase 1

Symbol

uhmk1 Nomenclature History

Previous Names

zgc:153241

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable protein serine/threonine kinase activity and ribonucleoprotein complex binding activity. Predicted to be involved in peptidyl-serine phosphorylation; positive regulation of translational initiation; and regulation of protein export from nucleus. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in neuronal ribonucleoprotein granule and nucleus. Orthologous to human UHMK1 (U2AF homology motif kinase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With uhmk1 Human Ortholog

No data available

Associated With uhmk1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000504	RNA recognition motif domain
Domain	IPR000719	Protein kinase domain
Domain	IPR034371	UHMK1, RNA recognition motif
Family	IPR034372	Serine/threonine-protein kinase Kist
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily